Clinical Trial Protocol Registry and Library
Design, Analyze, Communicate: Working together to improve clinical study outcomes.
Focusing on research Protocols where the trial sites were located in low- and middle-income countries, this resource includes three ways to access the Protocol Library:
- A table of all of the clinical trial protocols included in the Protocol Library
- A downloadable Excel registry list of all the clinical trial protocols included in the Protocol Library
- The Protocol Library sorted into disease area folders to allow direct access to relevant protocols
Clinical Trial Protocol Registry Table
Use this table to filter the Protocol Library to access specific protocols.
Filter the resources using the dropdown menus. Select a column heading to sort. Click or tap on a row to view the full record
| First Principal Investigator | Protocol Title | Disease/Disease Area | Region of Study |
| Andrew, Nunn |
STREAMLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Asia |
| Danel, Christine |
ANRS 12136 TempranoLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Guy, Marks |
A Randomized controlled trial of community-based screening for tuberculosis (the ACT 3 studies)Link to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Asia |
| Graeme, Meintjes |
Pred-ART trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Mitj, Oriol |
Yaws elimination on Lihir Island, New Ireland Province, PNG: A proof of principle of Mass Drug Treatment with azithromycinLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Yaws | Oceania |
| Anne, Hansen |
Electricity-free Infant Warmer for Newborn ThermoregulationLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Hypothermia | Africa |
| Daniel, Roth |
Randomized placebo-controlled trial of maternal vitamin D supplementation during pregnancy and lactation to improve infant linear growth in Dhaka, BangladeshLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Stunting | Asia |
| Sharon, Greene |
Impact of Cryotherapy versus Loop Electrosurgical Excision Procedure (LEEP) on Recurrence of Cervical Intraepithelial Neoplasia and HIV-1 Cervical Shedding among HIV-positive WomenLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Maternal | Africa |
| Firdausi, Qadri |
An individually randomized, placebo-controlled trial to measure the protection conferred by a single dose regimen of bivalent, killed, whole cell oral cholera vaccine (Shanchol<99>) in Dhaka, BangladeshLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Cholera | Asia |
| Sheila, Isanaka |
Randomized, double-blind, placebo-controlled phase III clinical trial to assess the efficacy and safety of a pentavalent rotavirus vaccine (BRV-PV) against severe rotavirus gastroenteritis among infants in NigerLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Rotavirus | Africa |
| Mila, Shakya |
Assessing the impact of a Vi-Polysaccharide Conjugate Vaccine in preventing typhoid infections among Nepalese children <96> a Phase III trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Typhoid | Asia |
| Kate, Winskell |
A Mobile Phone Game to Prevent HIV among Young AfricansLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
| Helen, Ayles |
A Study of the HIV Prevention Trials NetworkLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
| Diane, Havlir |
Sustainable East Africa Research in Community Health (SEARCH)Link to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
| William, Venter |
A 96-week Randomised, Phase 3 Non-inferiority Study of DTG + TAF + FTC Compared with DTG + TDF + FTC and EFV + TDF + FTC in Patients Infected with HIV-1 Starting First-line Antiretroviral TherapyLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
| Nel, Annalene |
A MULTI-CENTRE, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE II LONG-TERM SAFETY TRIAL OF A DAPIVIRINE VAGINAL MATRIX RING IN HEALTHY HIV-NEGATIVE WOMENLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
| Thuy, Le |
Itraconazole versus Amphotericin B for the Treatment of PenicilliosisLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Asia |
| Sle, Molloy |
A randomised controlled trial of oral fluconazole plus flucytosine versus amphotericin B-based therapy, for one or two weeks, for initial treatment of HIV-associated cryptococcal meningitisLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Meningitis | Africa |
| Merlin, Robb |
HIV-1 Prevalence, Incidence, Cohort Retention, and Host Genetics and Viral Diversity in Cohorts in East Africa and ThailandLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Asia |
| Niklaus, Labhardt |
Same-day antiretroviral therapy versus clinic referral and pre-ART counselling during home-based HIV testing in rural Lesotho (CASCADE trial): An open-label randomized controlled trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
HIV | Africa |
Downloadable Clinical Trial Protocol Registry
Download the Clinical Trial Protocol Registry to access a detailed Excel spreadsheet of all the publicly available global health protocols included in the Protocol Library and the links to access them.
Protocol Library
The Protocol Library includes publicly available global health trial protocols (sorted into disease area folders).
Please note: Implementors of studies should also always refer to relevant regulatory standards and guidelines (e.g. FDA, EMA) to assist with study/protocol design.
