Welcome

Clinical studies are the key source of knowledge in the field of global health. However, for a variety of reasons, many studies end without informative results, meaning that the resources that went into them did not improve or save lives.

The Design, Analyze and Communicate (DAC) program at the Gates Foundation was created to maximize the informativeness and impact of global health clinical research. The DAC Trials site hosts resources and tools funded by the DAC team, including an evidence-based catalogue of best practices, assessments, open-source simulation software and more. These resources and tools can benefit the broader global health clinical research community, not only Gates Foundation grantees, so we have made them publicly available.

Click on the links below to enter each area or focused area, respectively, or navigate using the drop-down menus in the bar above.

Created with Raphaël 2.1.2
Created with Raphaël 2.1.2Created with Raphaël 2.1.2
Find out more about the Design, Analyze and Communicate (DAC) Program. What is it and why is it needed?
Find answers to Frequently Asked Questions.
Apply DAC Tools, including the DAC Assessment Tool and Mediana’s Clinical Trial Simulation Tool, to your study.
DAC Tools and resources
Learn about the DAC Process and associated tools.
Access the DAC Best Practices, robust clinical study methods, for design, analysis, and communication.
Created with Raphaël 2.1.2
Created with Raphaël 2.1.2
Created with Raphaël 2.1.2
Created with Raphaël 2.1.2

Please note: Implementors of studies should also always refer to relevant regulatory standards and guidelines (e.g. FDA, EMA) to assist with study/protocol design.