Clinical Trial Protocol Registry and Library
Design, Analyze, Communicate: Working together to improve clinical study outcomes.
Focusing on research Protocols where the trial sites were located in low- and middle-income countries, this resource includes three ways to access the Protocol Library:
- A table of all of the clinical trial protocols included in the Protocol Library
- A downloadable Excel registry list of all the clinical trial protocols included in the Protocol Library
- The Protocol Library sorted into disease area folders to allow direct access to relevant protocols
Clinical Trial Protocol Registry Table
Use this table to filter the Protocol Library to access specific protocols.
Filter the resources using the dropdown menus. Select a column heading to sort. Click or tap on a row to view the full record
| First Principal Investigator | Protocol Title | Disease/Disease Area | Region of Study |
| Rubhana, Raqib |
A Phase 1 Randomized, Double-Blinded, Placebo-controlled, Dose-Escalation Study to Assess the Safety, Tolerability and Immunogenicity of Live Attenuated, Oral Shigella WRSS1 Vaccine in Bangladeshi ToddlersLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Shigellosis | Asia |
| Mauro, Sancovski |
A Post-marketing, Observational, Retrospective Study to Assess the Safety of RefortrixTM (Tdap) When Administered During Pregnancy in a Maternal Immunization Program in Brazil.Link to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tdap | South America |
| Firdausi, Qadri |
A Randomized, Double-blind, Placebo-controlled Study evaluating the safety, tolerability, and immunogenicity of an oral inactivated ETEC Vaccine (ETVAX) alone and together with dmLT adjuvant in descending age groups in BangladeshLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
E. coli | Asia |
| Nicola, Low |
Pivotal study to evaluate the immunogenicity and safety of a measles vaccine given by aerosolized inhalation: randomized controlled trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Measles | Asia |
| Robert, Heyderman |
Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Group B Strep | Africa |
| Franco, Piazza |
A Phase 1b, Randomized, Double-blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety and Immunogenicity of the ID93 + GLA-SE Vaccine in BCG-Vaccinated Healthy AdultsLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Mark, Hatherill |
A Randomized, Placebo Controlled, Partially Blinded Phase II Study to Evaluate Safety, Immunogenicity, and Prevention of Infection with Mycobacterium tuberculosis of AERAS-404 and BCG Revaccination in Healthy AdolescentsLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Dawson, Rodney |
A Phase 2 Open?Label Partially Randomized Trial to Evaluate the Efficacy, Safety and Tolerability of combinations of bedaquiline, moxifloxacin, PA?824 and pyrazinamide during 8 weeks of treatment in Adult Subjects with Newly Diagnosed Drug?Sensitive or Multi Drug? Resistant, Smear?Positive Pulmonary Tuberculosis.Link to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Jennifer, Keiser |
Efficacy and safety of a single dose regimen and a multi dose regimen of mebendazole against hookworm infections in children: a randomized controlled trialLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Hookworm | Africa |
| Carlos, Morillo |
A randomized double-blind placebo-controlled trial of benznidazole in patients with chronic Chagas<92> heart diseaseLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Chagas | South America |
| Xavier, Sez Llorens |
A Phase II, double-blind, controlled trial to assess the Safety and Immunogenicity of different schedules of Takeda<92>s Tetravalent Dengue Vaccine Candidate (TDV) in healthy subjects aged between 2 and <18 years and living in dengue endemic countries in Asia and Latin AmericaLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Dengue | Multi |
| Gary, Weil |
Community Based Safety Study of 2-drug (Diethylcarbamazine and Albendazole) versus 3-drug (Ivermectin, Diethylcarbamazine and Albendazole) Therapy for Lymphatic Filariasis in HaitiLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Filariasis | North America |
| Gary, Weil |
Community Based Safety and Efficacy Study of 2-drug (Diethylcarbamazine and Albendazole) versus 3-drug (Ivermectin, Diethylcarbamazine and Albendazole) Therapy for Lymphatic Filariasis in IndonesiaLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Filariasis | Asia |
| Gary, Weil |
Community Based Safety Study of 2-drug (Diethylcarbamazine and Albendazole) versus 3-drug (Ivermectin, Diethylcarbamazine and Albendazole) Therapy for Lymphatic Filariasis in Papua New GuineaLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Filariasis | Oceania |
| Jean, Humphrey |
Sanitation Hygiene Infant Nutrition Efficacy ProjectLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Stunting | Africa |
| Maitland, Kathryn |
TRACTLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Anemia | Africa |
| Jeremy, Keenan |
Mortality Reduction After Oral AzithromycinLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Pneumonia | Africa |
| Elizabeth, Alexander |
A Phase 3, Randomized, Double-Blind, Double-Dummy Study to Compare the Efficacy and Safety of Oral Lefamulin (BC-3781) Versus Oral Moxifloxacin in Adults With Community-Acquired Bacterial PneumoniaLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Pneumonia | Multi |
| Dereck, Tait |
A phase IIb, double-blind, randomised, placebocontrolled study to evaluate the efficacy, safety, and immunogenicity of GSK Biologicals’ candidate tuberculosis (TB) vaccine GSKLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
| Sara, Suliman |
A Phase I/IIa Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Study to Evaluate the Safety and Immunogenicity of AERAS-456 in HIV-negative Adults with and without Latent Tuberculosis InfectionLink to ProtocolFirst Principal Investigator Disease/Disease Area Region of Study Site Countries Link to Protocol Source of Protocol Approximate Page Count Date of Scientific Journal Publication Scientific Journal Publication |
Tuberculosis | Africa |
Downloadable Clinical Trial Protocol Registry
Download the Clinical Trial Protocol Registry to access a detailed Excel spreadsheet of all the publicly available global health protocols included in the Protocol Library and the links to access them.
Protocol Library
The Protocol Library includes publicly available global health trial protocols (sorted into disease area folders).
Please note: Implementors of studies should also always refer to relevant regulatory standards and guidelines (e.g. FDA, EMA) to assist with study/protocol design.
